Mini review: Micro RNA in nasopharyngeal carcinoma

Lao Duc Thuan; Nguyen Hoang Anh Tuan; Nguyen Van Truong; Nguyen Huu Dung; Le Huyen Ai Thuy

6 (1) 2016

Mini review: Micro RNA in nasopharyngeal carcinoma

Author - Affiliation:

Lao Duc Thuan - Ho Chi Minh City Open University , Vietnam

Nguyen Hoang Anh Tuan - University of Science, Vietnam National University Ho Chi Minh City , Vietnam

Nguyen Van Truong - Ho Chi Minh City International University, Vietnam National University HCMC , Vietnam

Nguyen Huu Dung - Cho Ray Hospital , Vietnam

Le Huyen Ai Thuy - Ho Chi Minh City Open University , Vietnam

Corresponding author: Lao Duc Thuan - thuy.lha@ou.edu.vn

Abstract

Nasopharyngeal carcinoma (NPC) is a highly invasive and malignant tumor of the nasopharynx, the uppermost region of the pharynx, gravitating toward Southeast Asia, especially Vietnam. The etiology of NPC is suggested to be involved to several genetic susceptibility and environmental factors. miRNAs (microRNA), the short non-coding RNA molecular, have been reported that played important roles, as oncogene and/or tumor suppressor gene, in progression and development of NPC. In this review, we summarized the role of miRNAs in NPC and their potential use as biomarkers for early prognosis and diagnosis of NPC as well as therapeutic agent of NPC in future.

Keywords

miRNA; nasopharyngeal carcinoma; biomarkers; therapeutic agents

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References

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