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7 (1) 2017

Antibacterial activity of crude methanolic and fractionated extracts of Aaptos suberitoides


Author - Affiliation:
Bui Thi Kim Ly - Biotechnology Center of Ho Chi Minh City, Vietnam , Vietnam
Ngo Thi Phuong Dung - Biotechnology Center of Ho Chi Minh City, Vietnam , Vietnam
Nguyen Quoc Huy - Biotechnology Center of Ho Chi Minh City, Vietnam , Vietnam
Phan Thi Kim Tram - Biotechnology Center of Ho Chi Minh City, Vietnam , Vietnam
Hoang Thanh Chi - Biotechnology Center of Ho Chi Minh City, Vietnam , Vietnam
Nguyen Hai Dang - Hutech University of Technology, Ho Chi Minh City , Vietnam
Corresponding author: Bui Thi Kim Ly - buithikimly1201@gmail.com

Abstract
In this research, we at the first time assessed antibacterial effects of methanolic crude and fractionated extracts from the marine sponge, Aaptos suberitoides against three bacterial strains including E. coli., S. aureus, B. cereus. The anti-bacterial assays were carried out by the disc diffusion method to test the anti-bacterial activity of different concentrations of methanolic crude of A. suberitoides against the indicator bacterial pathogens. The results indicated that extracts of A. suberitoides exhibited anti-microbial activity against all tested bacterial strains in concentrationdependent manner. Moreover, we showed that the majority of the active compound was in the polar fractions.

Keywords
antibacterial; Aaptos suberitoides; active compound; marine organisms.

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References

Aneiros A, Garateix A (2004). Bioactive peptides from marine sources: pharmacological properties and isolation procedures. J Chromatogr B Analyt Technol Biomed Life Sci, 803, 41-53.


Ammerman J, Fuhrman J, Hagström Å, Azam F (1984). Bacterioplankton growth in seawater: I. Growth kinetics and cellular characteristics in seawater cultures. Marine Ecology Progress Series, 31-39.


Ammar MSA, Ghobashi AA, Omran MA, Shaaban AM (2007). Status of Coral Reef Affected by Different Impacts in Some Sites in the Red Sea.


Bassetti M, Merelli M, Temperoni C, Astilean A (2013). New antibiotics for bad bugs: where are we? Ann Clin Microbiol Antimicrob, 12, 22.


Barboza NM, Medina DJ, Budak-Alpdogan T, Aracil M, Jimeno JM, et al. (2012). Plitidepsin (Aplidin) is a potent inhibitor of diffuse large cell and Burkitt lymphoma and is synergistic with rituximab. Cancer Biol Ther, 13, 114-122.


Chin Y-W, Balunas MJ, Chai HB, Kinghorn AD (2006). Drug discovery from natural sources. The AAPS Journal, 8, E239-E253.


Kang HK, Seo CH, Park Y (2015). Marine Peptides and Their Anti-Infective Activities. Marine Drugs, 13, 618-654.


Martin LP, Krasner C, Rutledge T, Ibanes ML, Fernandez-Garcia EM, et al. (2013). Phase II study of weekly PM00104 (ZALYPSIS((R))) in patients with pretreated advanced/metastatic endometrial or cervical cancer. Med Oncol, 30, 627.


Rice LB (2006). Antimicrobial resistance in gram-positive bacteria. Am J Med 119: S11-19; discussion S62-70.


Tsoukalas N, Tolia M, Lypas G, Panopoulos C, Barbounis V, et al. (2014). Complete remission of a recurrent mesenteric liposarcoma with rare histological features following the administration of trabectedin. Oncology Letters, 7, 47-49.


Valliappan K, Sun W Fau (2014). Li Z, Li Z Marine actinobacteria associated with marine organisms and their potentials in producing pharmaceutical natural products.


Zilinskas RA (1992). Marine Biotechnology and the Third World: Research and Applications. Conference Proceedings Series: Harnessing Biotechnology for the 21st Century. Washington D.C: American Chemical Society.



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