Antioxidant activity of isolated compounds from ethyl acetate extract of Bruguiera parviflora

Bui Thanh Tung; Nguyen Thi Le Thuy

doi:10.46223/HCMCOUJS.tech.en.12.2.2329.2022

Authors

Bui Thanh Tung
Vietnam Academy of Science and Technology (VAST), Ho Chi Minh City
Nguyen Thi Le Thuy thuy.ntl@ou.edu.vn
Ho Chi Minh City Open University, Ho Chi Minh City

DOI:

https://doi.org/10.46223/HCMCOUJS.tech.en.12.2.2329.2022

Keywords:

antioxidant, bioactivity, Bruguiera parviflora, DPPH, mangrove plant, phytochemical

Abstract

Bruguiera parviflora belongs to Bruguiera genus, which possesses several biological activities such as antidiabetic, anti-inflammatory, and antioxidant. Phytochemical investigation of the ethyl acetate extract from Bruguiera parviflora leaves was carried out bioassay-guided isolation and obtained three known compounds, namely kochioside A (1), oleanolic acid (2) and quercitrin (3). The chemical structures of isolated compounds were identified by spectroscopic method and comparison with previously published data. All isolated compounds were evaluated for antioxidant activity with the free radical scavenging ability on 1,1-diphenyl-2-picrylhydrazyl (DPPH). Among them, quercitrin (3) was the most potent compound against DPPH radical with the IC50 value of 16.4 ± 0.2 µg/mL, compared to vitamin C, which was used as a positive control.

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